28 December 2022
IV thrombolysis, i.e. clot buster, can be given to patients presenting within 4.5 hours of symptom onset. Currently, the golden hour is 4.5 hours from time of stroke symptom onset; the earlier the treatment, the better the outcome. The benefits of clot buster in patients with acute ischemic stroke are time-dependent, and guidelines recommend a door-to-needle time of 60 minutes or less.